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The editorial heart of the Index

Hype vs Science

The gap between cultural momentum and scientific momentum is the most revealing number the Index produces. A wide positive gap means public enthusiasm is running ahead of the evidence. A narrow gap on a high-scoring topic means attention and evidence are aligned. Ratings are derived from the gap and the scientific score — see the methodology page for exact thresholds.

TopicCulturalScientificGapRating
Methylene blue749+65Pure hype
Exosome therapy5112+39Speculative
Cold plunge6834+34Speculative
NMN / NR4928+21Emerging evidence
Sleep tracking7055+15Emerging evidence
Vagus nerve stimulation5440+14Emerging evidence
Biological age testing5844+14Emerging evidence
Creatine9178+13Science-backed
GLP-1 neuroprotection7261+11Science-backed
Sauna6360+3Science-backed
Zone 2 training6664+2Science-backed
Intermittent fasting4762-15Science-backed